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Glenmark Pharmaceuticals and SaNOtize Announce Peer Reviewed Publication of Its Phase 3 Clinical Trials on SaNOtize’s Novel Nitric Oxide Nasal Spray for COVID-19 in Lancet Journal

–  The Lancet Regional Health Southeast Asia publishes the successful phase 3 clinical trial results of Nitric Oxide Nasal Spray.

–  Phase 3 trial of Nitric Oxide Nasal Spray administered to adult COVID-19 patients in India met the key endpoints and demonstrated reductions of viral load of 94% in 24 hours and 99% in 48 hours.

–  Nitric Oxide Nasal Spray was safe and well tolerated in COVID-19 patients.

–  Following positive results and regional approvals, Glenmark launched this nasal spray in India under the brand name FabiSpray® and in Singapore and Hong Kong under the brand name VirX™.

MUMBAI, India and VANCOUVER, BC, July 13, 2022 /PRNewswire/ — Glenmark Pharmaceuticals Limited (Glenmark), an innovation-driven, global pharmaceutical company, and SaNOtize Research and Development Corp, today announced that The Lancet Regional Health Southeast Asia (TLRHSEA) – peer reviewed, high impact journal published the successful phase 3 clinical trial results of SaNOtize’s Nitric Oxide Nasal Spray (NONS) study titled: ‘SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial’.

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https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(22)00046-4/fulltext

“We are excited to publish the study of the novel Nitric Oxide Nasal Spray, which positively impacts the lives of people, in The Lancet group of journals. The robust double-blind trial demonstrated significant efficacy and remarkable safety of NONS. This therapy has the potential to make a crucial contribution to COVID-19 management, with its ease of use in the current highly transmissible phase of pandemic,” said Dr. Monika Tandon, Senior VP & Head – Clinical Development, Glenmark Pharmaceuticals Ltd.

The study demonstrated that patients who received NONS had significant reduction in viral load within 24 hours, which was sustained over seven days of treatment. Viral load was reduced by 93.7% within 24 hours and by 99% within 48 hours of treatment with NONS. The average change from baseline in log viral RNA load through the entire treatment duration was statistically superior with NONS compared to placebo. Similar results were observed in vaccinated and unvaccinated populations. The study was conducted during the delta and omicron surges. Key secondary endpoints including clinical improvement assessed by WHO Clinical Progression Scale Score and extent/rapidity of virologic recovery was demonstrated in patients using NONS. The median time to virological cure was three days in the NONS group and seven days in the placebo group after start of treatment (four days sooner). The exploratory evaluation of the proportion of immediate contacts having a positive COVID-19 test or becoming symptomatic, remained nearly the same in the NONS group while it numerically increased in the placebo group over the treatment. 

“The Phase 3 study results strongly support the safety and efficacy of NONS in the treatment of COVID-19 and its known variants,” said Gilly Regev, PhD, SaNOtize Co-Founder and CEO. “Nitric oxide blocks entry into the nasal passage, kills the virus, and stops its replication, which is why viral load is reduced so rapidly with NONS. Viral load has been linked to infectivity, poorer health outcomes, and complications from long COVID. The evidence is mounting that NONS represents an effective, well tolerated antiviral treatment that significantly shortens the course of COVID-19.”

Study Design

The study was conducted by Glenmark in 306 vaccinated and non-vaccinated adults of symptomatic mild COVID-19 across 20 clinical sites in India. This randomized, double-blind phase 3 clinical trial evaluated a seven-day treatment of NONS plus standard of care versus placebo nasal spray plus standard care in patients with symptomatic COVID-19. The primary outcome measure of nasal SARS-CoV-2 RNA accelerated clearance was used to assess the efficacy of this transformational NONS in high-risk patients (unvaccinated, or 45 years of age, or had one or more comorbidities) after seven days of treatment. Exploratory evaluation of NONS in prevention of infection in immediate contacts of these COVID-19 patients was also evaluated.

NONS treatment was found to be well tolerated, establishing an advantage of locally acting nasal therapy. None of the patients reported any moderate or severe adverse events. There were no clinically significant changes from baseline observed in methemoglobin suggesting lack of systemic availability of nitric oxide from nasal spray. Additionally, neither nasal vasodilation symptoms nor systemic vasodilation signs were observed in either treatment.

Strategic Partnership with SaNOtize

In July 2021, Glenmark entered into an exclusive long term strategic partnership with Canadian biotech firm SaNOtize, to manufacture, market and distribute its breakthrough Nitric Oxide Nasal Spray for COVID-19 treatment in India and other Asian markets including Singapore, Malaysia, Hong Kong, Taiwan, Nepal, Brunei, Cambodia, Laos, Myanmar, Sri Lanka, Timor-Leste and Vietnam.

Global Approvals for NONS

Glenmark launched NONS under the brand name FabiSpray® in February 2022, after receiving manufacturing and marketing approval from the Drugs Controller General of India (DCGI) as part of the accelerated approval process. NONS has already received a CE mark in Europe, which is an equivalent of marketing authorization in case of a Medical Device. By virtue of the CE mark, SaNOtize has permission to launch NONS in the EU. NONS is also approved and being sold in Singapore, Hong Kong, Israel, Thailand, Indonesia and Bahrain, under the name enovid™ or VirX™. Outside of India, NONS has also been approved globally for protection against viruses, including SARS COV-2.

About Glenmark Pharmaceuticals Ltd

Glenmark Pharmaceuticals Ltd. (BSE: 532296 | NSE: GLENMARK) is an innovation-driven global pharmaceutical company with a presence across Specialty, Generics and OTC businesses. It focuses on the key therapeutic areas of respiratory, dermatology and oncology. The company has 10 world-class manufacturing facilities spread across 4 continents and operations in over 80 countries. Glenmark is ranked among the world’s top 100 biopharmaceutical companies (Top 100 Companies Ranked by Pharmaceutical Sales, 2020, by In Vivo/Scrip 100) and among the world’s top 50 companies in the off-patent sector (Top 50 Generics and Biosimilars Companies ranked by Sales, 2020, by Generics Bulletin/In Vivo). The company was listed on the Dow Jones Sustainability Index (DJSI), one of the world’s most respected and widely accepted sustainability benchmarks, under the category of emerging markets (2021) for the fourth consecutive year. For more information, visit www.glenmarkpharma.com.

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About SaNOtize

SaNOtize Research & Development Corp. is a pharmaceutical company based in Vancouver, BC, commercializing the multi-faceted antimicrobial properties of a liquid producing nitric oxide. The company has developed and patented a Nitric Oxide Releasing Solution platform technology (NORS) to treat and prevent upper respiratory and topical infections. For more information, visit www.SaNOtize.com. Follow us on social: LinkedIn, Twitter.

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Firstsource Partners with Typeface to Launch Agentic Marketing Services

New full-stack offering turns content operations into an agentic growth engine

NEW YORK and MUMBAI, India, April 30, 2026 /PRNewswire/ — Firstsource Solutions Limited (NSE: FSL) (BSE: 532809), an RP-Sanjiv Goenka Group company, today announced the launch of a new offering — Agentic Marketing Services — in partnership with Typeface, the marketing orchestration engine for the world’s leading enterprises. The offering is designed to help enterprises move from marketing ambition to scale by transforming, implementing, and operating AI-native marketing systems. It transforms marketing operations into a scalable growth engine and delivers measurable top-line revenue growth beyond operational efficiency alone.

 

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Agentic AI is redefining how enterprises think about the customer lifecycle, and marketing content sits at the center of that transformation. Enterprises deploying AI-driven personalization are seeing up to 40% higher revenue compared to their peers. Content operations is both a growth lever and an efficiency play for CMOs: roughly 30% of CMO budgets go to content; approximately 55% of content work is manual — resizing, localization, brand compliance — while 90% of those manual workflows can be AI-enabled.

“At Firstsource, our approach has been about moving beyond traditional boundaries to build adaptive, intelligence-led ecosystems that deliver measurable outcomes. Content operations is now the most disrupted layer of the modern marketing stack, with Large Language Models reshaping the entire value chain — from ideation and production to governance and distribution — making it both the biggest near-term efficiency opportunity and the most exposed surface area in enterprise marketing,” said Ritesh Idnani, MD and Chief Executive Officer of Firstsource.

“CEOs and CMOs are not looking for a consultancy that hands off a roadmap or an agency that operates in silos — they want a partner who can transform, implement, and operate marketing systems end-to-end. By combining micro-segmentation, personalization, and deep industry context, we help clients build acquisition, engagement, and retention engines that are intelligent, compliant, and scalable. Typeface brings the AI technology to generate personalized, on-brand, compliant content at scale, and Firstsource brings deep experience in customer operations, especially in regulated industries like banking, financial services, healthcare, and retail. Together, we enable enterprises to plan, build, and run modern marketing — turning content operations into a compounding growth engine and delivering outcomes, not just effort.”

The partnership extends the capabilities announced with Typeface’s recent Marketing Orchestration Engine launch — bringing governed AI systems into full-stack marketing operations for regulated enterprises.

“AI only transforms marketing when it’s embedded into the workflows that drive real customer outcomes,” said Abhay Parasnis, Founder & CEO of Typeface. “Firstsource brings deep industry expertise and operational rigor in highly regulated environments. Together, we’re helping enterprises turn AI ambition into operational reality, embedding governed intelligence into the systems that power durable growth.” 

While Typeface provides the orchestration layer that unifies brand intelligence, AI agents, and enterprise systems, Firstsource brings the operational expertise and insights to enable effective decision making and implement and run these systems in complex, regulated environments. Together, they redesign how growth is driven — focusing on the moments, segments, and mechanisms that truly move the needle — enabling enterprises to shift from fragmented activity to scalable, revenue-led execution.

Industry view

“In retail, seasonality and micro-segmentation are where revenue is won or lost. Every peak moment demands thousands of personalized variants across marketing, service, and customer operations — and the retailers who get this right see real movement on acquisition, conversion, and retention, not just efficiency. What makes the Firstsource–Typeface offering different is that it is not another tool — it is an operating capability. Pairing agentic AI with embedded marketing operations is exactly what retailers need to move from broad campaigns to true lifecycle-driven engagement. For the industry, this is a meaningful step-change in how growth gets engineered.”

– Dave Kimbell, Ex-CEO Ulta Beauty; Firstsource Advisory Board Member

“Healthcare payers sit on a real paradox: a huge share of member communication is locked inside PHI and claims workflows where the rules are clear and rightly strict — but the biggest lever on affordability lives outside that envelope, in how payers engage members on wellness, prevention, plan literacy, and proactive disease management. That is a white-space opportunity the industry has barely touched. This is where marketing AI services can genuinely move the needle. With micro-segmentation and agentic content, payers can reach the right member with the right nudge at the right moment — entirely within compliant, non-PHI pathways — and shift the engagement model from acquisition and retention to lifelong wellness. That is how you make healthcare more affordable, improve member experience, and strengthen the economics of the plan at the same time. The Firstsource–Typeface offering is one of the few capabilities purpose-built to operate at that intersection of compliance, personalization, and outcomes.”

– Paul Sanford, Ex-EVP Operations, Cigna Group; Firstsource Advisory Board Member

About Firstsource

Firstsource Solutions Limited, an RP-Sanjiv Goenka Group company (NSE: FSL) (BSE: 532809), is a global intelligence partner to enterprises across healthcare, banking and financial services, communications, media, technology, retail, and utilities. Its inch-wide, mile-deep practitioners work collaboratively to reimagine business process management.

With operations across the US, UK, India, Philippines, Mexico, Romania, Trinidad & Tobago, South Africa, and Australia, Firstsource combines over twenty-five years of domain expertise with an agent-first delivery model to design, build, and operate intelligent enterprise operations. Through its Intelligence That Operates promise—powered by Kairos, the operating system that makes it real—the company unifies consulting, implementation, and operations into a single full-stack engagement and underwrites outcomes, not effort, turning deep domain intelligence into a compounding operational advantage for firms in the world’s most regulated industries. (www.firstsource.com)

About Typeface

Typeface is a marketing orchestration engine for the world’s leading enterprises, coordinating brand intelligence, AI agents, and enterprise systems across cross-channel marketing operations. Built for large organizations, Typeface combines shared brand intelligence, governed agent workflows, and deep enterprise integration at scale — connecting seamlessly with platforms like Salesforce, Microsoft, and Google — to help teams scale what works without sacrificing quality or control. Trusted by Fortune 500 companies, Typeface enables organizations to operationalize AI inside real marketing workflows, turning brand standards, approvals, and performance signals into coordinated systems that improve over time. Typeface is backed by Lightspeed, GV, Salesforce Ventures, Madrona, Menlo, and M12, and has been recognized by Fast Company, Gartner, TIME, LinkedIn, and Adweek as a leader in AI for marketing. Learn more at www.typeface.ai.

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Shaping Future-Ready School Leaders: Woxsen University Leads Design Thinking Initiative for Principals

HYDERABAD, India, April 30, 2026 /PRNewswire/ — The School of Arts and Design at Woxsen University, in collaboration with the Public-School Principals’ Association (PSPA), conducted a Principal Leadership Programme on April 27, bringing together 30 principals from leading schools across Hyderabad for an immersive, design-led learning experience focused on rethinking leadership in contemporary education.

Participating institutions included Delhi Public School, Sloka International School (Tukkuguda), Jain Heritage Cambridge School, AVN Vida International School, CMR School (Medchal), and Gitanjali High School, among others. Designed as a hands-on, studio-based workshop, the programme moved beyond traditional formats, enabling participants to engage in collaborative problem-solving, systems thinking, and real-world leadership challenges.

The programme was delivered by Woxsen’s Centre for Learning Design (CLD) and the David Dunne Design Thinking Lab, and was guided by the university’s ERS (Ethics, Responsibility and Sustainability) framework, reflecting an integrated and purpose-driven approach to leadership development.

Through guided design thinking exercises, principals explored new approaches to decision-making, innovation in school ecosystems, and building student-centric learning environments. The interactive format encouraged peer exchange and practical application, making the experience directly relevant to institutional leadership.

Rajendra Prasad, President of the PSPA, said, “The School Principals’ Leadership Workshop at Woxsen University was well organized and delivered with great impact. The sessions were highly engaging and insightful, and the programme received overwhelming positive feedback from participants for both its content and overall experience.”

Dr. Ashok Pandey, Member of the PSPA Leadership Team, shared, “An inspiring day at the picturesque Woxsen University campus, engaging with exceptional school leaders committed to designing the schools of tomorrow.” 

Dr. Adity Saxena, Dean, School of Arts & Design, said, “This programme is aligned with Woxsen’s core pillar of Ethics, Responsibility and Sustainability, reinforcing our commitment to purpose-driven education. We see our role as bridging ideas, institutions, and impact in education, and we are grateful to PSPA and Rajendra Prasad for this meaningful collaboration.”

The initiative reflects Woxsen University’s commitment to strengthening the school education ecosystem in Telangana by building leadership capacity and fostering future-ready thinking among educators. Following the workshop, the PSPA leadership team engaged in a strategic discussion with Dr. Adity Saxena to explore future collaboration opportunities.

Building on the momentum of the programme, Woxsen University and PSPA are exploring the launch of a structured Principal Leadership Certificate Programme. The proposed initiative aims to institutionalize leadership development for school heads and further strengthen the region’s education ecosystem through sustained, practice-oriented engagement.

About Woxsen University, Hyderabad

Woxsen University, located in Hyderabad, is one of the first private universities in the state of Telangana, India. Renowned for its 200-acre state-of-the-art campus and infrastructure, Woxsen University offers new-age, disruptive programs in the fields of Business, Technology, Arts & Design, Architecture, Law, and Liberal Arts & Humanities. Woxsen also houses Asia’s largest Sports Infrastructure, spread over 60 acres. With 175 Global Partner Universities and a strong industry connect, Woxsen is recognized as one of the top universities for Academic Excellence and Global Edge. Woxsen has also secured the QS Business Masters World Ranking 2025, Rank #9 All India, Top 100 B-Schools by Times B-School Ranking 2025, Rank #6, Asia Pacific, Bloomberg Best B-School, and features in India’s Best B-Schools beyond IIMs by Dalal Street Investment Journal 2025, in 4th consecutive year. Woxsen is ranked as one of the Top Professional Colleges in India by Outlook I-CARE for its undergraduate programs, securing All India Rank 12 among the Top 130 BBA Private Institutes, All India Rank 20 among the Top 160 B.Tech Private Institutes, All India Rank 3 among the Top 25 Design Private Institutes, and All India Rank 3 among the Top 30 B. Arch Private Institutes.

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HarperCollins is proud to announce the publication of The Book of Daily Brilliance: 111 Days to Transformation by Pamela Puja Kirpalani

Published by HarperCollins

Hardback | Non-Fiction/Self-Help | 140 pp | INR 399

Available wherever books are sold | Releasing on 24 April 2026

NEW DELHI, April 29, 2026 /PRNewswire/ — HarperCollins Publishers India is thrilled to announce the publication of The Book of Daily Brilliance: 111 Days to Transformation by Pamela Puja Kirpalani, a practical guide towards a spiritual and psychological transformation.

ORDER HERE

ABOUT THE BOOK

Everyone in the world has good days and bad days. But what if there was a way to unleash one’s radiant self every day? Something simple yet profound—something the reader could reach for every day to centre themselves and remember what really matters.

The Book of Daily Brilliance is designed to speak to the heart and the highest self. Meant to be read over 111 days and covering topics that resonate with all—relationships, self-worth, love, pain, abundance, manifestation, surrender and much more—this daily reader will guide the one through a gentle yet powerful spiritual and psychological journey.

There is no fixed start date. No pressure to be perfect. If a day is skipped or there is a pause for a while, that is okay. All that’s needed to do is come back when it feels right. For those who choose to commit to the 111-day journey, the experience reveals the unfolding of a deeper truth within. 

So, take a deep breath. Open the page to Day 1 and let this be an invitation to return to oneself —one day, one page, one insight at a time.

Pamela Puja Kirpalani says, “One page can really just change the way you show up for your life. I wrote The Book of Daily Brilliance to be something you return to, not just read once — a daily pause that brings clarity, perspective and healing. In a fast-paced world, I believe even a single mindful page a day can create powerful inner psychological shifts. This 111 Daily Reader is my way of helping people reconnect with themselves— and if it helps someone feel more present, more grounded, and more like themselves, then it has done exactly what I hoped it would.”

Sachin Sharma, Publisher, HarperCollins India, says, The Book of Daily Brilliance offers a perfect pause amidst the busyness of life. Readers will appreciate how the book gently guides them through a journey of transformation—without any pressure—one step, one day at a time.”

ABOUT THE AUTHOR

Pamela Puja Kirpalani is the Founder of Inner High Living and a distinguished thought leader in the world of behavioural psychology and neuro-behaviour. Her vision materialized as she started coaching individuals, couples and parents on achieving their goals initially using Neuro-linguistic Programming (NLP) as a modality. She is certified by ABNlp (Australian Board of Neuro-Linguistic Programming), IEMT (Integrated Eye Movement Technique) Practitioner, member of the APSS Singapore and the NLP Association of Singapore.

ABOUT HARPERCOLLINS INDIA

At HarperCollins Publishers India, we believe in telling the best stories and ensuring they reach the widest readership. We publish around 250 new books every year across 10 imprints, adding to a diverse catalogue of more than 2,000 titles across print and digital formats. Our authors include APJ Abdul Kalam, Agatha Christie, Amish Tripathi, Amitav Ghosh (Erasmus Prize 2024), Jhumpa Lahiri, Paulo Coelho, Raghuram Rajan, Sudha Murty, Ruskin Bond and many more.

HarperCollins India has been honoured with seven Publisher of the Year awards and proudly represents global publishers such as Harvard University Press, Lonely Planet, Oneworld, Nosy Crow, Usborne and National Geographic Children.

We have also been certified as a Great Place to Work for two consecutive years, a testament to our culture, creativity and people.

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