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Glenmark Pharmaceuticals and SaNOtize Announce Peer Reviewed Publication of Its Phase 3 Clinical Trials on SaNOtize’s Novel Nitric Oxide Nasal Spray for COVID-19 in Lancet Journal
– The Lancet Regional Health Southeast Asia publishes the successful phase 3 clinical trial results of Nitric Oxide Nasal Spray.
– Phase 3 trial of Nitric Oxide Nasal Spray administered to adult COVID-19 patients in India met the key endpoints and demonstrated reductions of viral load of 94% in 24 hours and 99% in 48 hours.
– Nitric Oxide Nasal Spray was safe and well tolerated in COVID-19 patients.
– Following positive results and regional approvals, Glenmark launched this nasal spray in India under the brand name FabiSpray® and in Singapore and Hong Kong under the brand name VirX™.
MUMBAI, India and VANCOUVER, BC, July 13, 2022 /PRNewswire/ — Glenmark Pharmaceuticals Limited (Glenmark), an innovation-driven, global pharmaceutical company, and SaNOtize Research and Development Corp, today announced that The Lancet Regional Health Southeast Asia (TLRHSEA) – peer reviewed, high impact journal published the successful phase 3 clinical trial results of SaNOtize’s Nitric Oxide Nasal Spray (NONS) study titled: ‘SARS-CoV-2 accelerated clearance using a novel nitric oxide nasal spray (NONS) treatment: A randomized trial’.
https://www.thelancet.com/journals/lansea/article/PIIS2772-3682(22)00046-4/fulltext
“We are excited to publish the study of the novel Nitric Oxide Nasal Spray, which positively impacts the lives of people, in The Lancet group of journals. The robust double-blind trial demonstrated significant efficacy and remarkable safety of NONS. This therapy has the potential to make a crucial contribution to COVID-19 management, with its ease of use in the current highly transmissible phase of pandemic,” said Dr. Monika Tandon, Senior VP & Head – Clinical Development, Glenmark Pharmaceuticals Ltd.
The study demonstrated that patients who received NONS had significant reduction in viral load within 24 hours, which was sustained over seven days of treatment. Viral load was reduced by 93.7% within 24 hours and by 99% within 48 hours of treatment with NONS. The average change from baseline in log viral RNA load through the entire treatment duration was statistically superior with NONS compared to placebo. Similar results were observed in vaccinated and unvaccinated populations. The study was conducted during the delta and omicron surges. Key secondary endpoints including clinical improvement assessed by WHO Clinical Progression Scale Score and extent/rapidity of virologic recovery was demonstrated in patients using NONS. The median time to virological cure was three days in the NONS group and seven days in the placebo group after start of treatment (four days sooner). The exploratory evaluation of the proportion of immediate contacts having a positive COVID-19 test or becoming symptomatic, remained nearly the same in the NONS group while it numerically increased in the placebo group over the treatment.
“The Phase 3 study results strongly support the safety and efficacy of NONS in the treatment of COVID-19 and its known variants,” said Gilly Regev, PhD, SaNOtize Co-Founder and CEO. “Nitric oxide blocks entry into the nasal passage, kills the virus, and stops its replication, which is why viral load is reduced so rapidly with NONS. Viral load has been linked to infectivity, poorer health outcomes, and complications from long COVID. The evidence is mounting that NONS represents an effective, well tolerated antiviral treatment that significantly shortens the course of COVID-19.”
Study Design
The study was conducted by Glenmark in 306 vaccinated and non-vaccinated adults of symptomatic mild COVID-19 across 20 clinical sites in India. This randomized, double-blind phase 3 clinical trial evaluated a seven-day treatment of NONS plus standard of care versus placebo nasal spray plus standard care in patients with symptomatic COVID-19. The primary outcome measure of nasal SARS-CoV-2 RNA accelerated clearance was used to assess the efficacy of this transformational NONS in high-risk patients (unvaccinated, or 45 years of age, or had one or more comorbidities) after seven days of treatment. Exploratory evaluation of NONS in prevention of infection in immediate contacts of these COVID-19 patients was also evaluated.
NONS treatment was found to be well tolerated, establishing an advantage of locally acting nasal therapy. None of the patients reported any moderate or severe adverse events. There were no clinically significant changes from baseline observed in methemoglobin suggesting lack of systemic availability of nitric oxide from nasal spray. Additionally, neither nasal vasodilation symptoms nor systemic vasodilation signs were observed in either treatment.
Strategic Partnership with SaNOtize
In July 2021, Glenmark entered into an exclusive long term strategic partnership with Canadian biotech firm SaNOtize, to manufacture, market and distribute its breakthrough Nitric Oxide Nasal Spray for COVID-19 treatment in India and other Asian markets including Singapore, Malaysia, Hong Kong, Taiwan, Nepal, Brunei, Cambodia, Laos, Myanmar, Sri Lanka, Timor-Leste and Vietnam.
Global Approvals for NONS
Glenmark launched NONS under the brand name FabiSpray® in February 2022, after receiving manufacturing and marketing approval from the Drugs Controller General of India (DCGI) as part of the accelerated approval process. NONS has already received a CE mark in Europe, which is an equivalent of marketing authorization in case of a Medical Device. By virtue of the CE mark, SaNOtize has permission to launch NONS in the EU. NONS is also approved and being sold in Singapore, Hong Kong, Israel, Thailand, Indonesia and Bahrain, under the name enovid™ or VirX™. Outside of India, NONS has also been approved globally for protection against viruses, including SARS COV-2.
About Glenmark Pharmaceuticals Ltd
Glenmark Pharmaceuticals Ltd. (BSE: 532296 | NSE: GLENMARK) is an innovation-driven global pharmaceutical company with a presence across Specialty, Generics and OTC businesses. It focuses on the key therapeutic areas of respiratory, dermatology and oncology. The company has 10 world-class manufacturing facilities spread across 4 continents and operations in over 80 countries. Glenmark is ranked among the world’s top 100 biopharmaceutical companies (Top 100 Companies Ranked by Pharmaceutical Sales, 2020, by In Vivo/Scrip 100) and among the world’s top 50 companies in the off-patent sector (Top 50 Generics and Biosimilars Companies ranked by Sales, 2020, by Generics Bulletin/In Vivo). The company was listed on the Dow Jones Sustainability Index (DJSI), one of the world’s most respected and widely accepted sustainability benchmarks, under the category of emerging markets (2021) for the fourth consecutive year. For more information, visit www.glenmarkpharma.com.
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About SaNOtize
SaNOtize Research & Development Corp. is a pharmaceutical company based in Vancouver, BC, commercializing the multi-faceted antimicrobial properties of a liquid producing nitric oxide. The company has developed and patented a Nitric Oxide Releasing Solution platform technology (NORS™) to treat and prevent upper respiratory and topical infections. For more information, visit www.SaNOtize.com. Follow us on social: LinkedIn, Twitter.
News Wire
teamLab Phenomena Abu Dhabi opens its doors to the public in Saadiyat Cultural District
- The innovative multi-sensory art experience redefines the boundaries of immersive art
- Purpose-built 17,000 sqm venue features transformative artworks unique to Abu Dhabi
- Opening music composed and performed by renowned Italian pianist Ludovico Einaudi
- teamLab Phenomena Abu Dhabi takes guests on a sensory-rich journey that transcends the ordinary and ignites curiosity for all
ABU DHABI, UAE, April 18, 2025 /PRNewswire/ — teamLab Phenomena Abu Dhabi officially opened its transformative multi-sensory art experience within Saadiyat Cultural District, an enriching addition to Abu Dhabi’s dynamic cultural and artistic landscape.
To view the Multimedia News Release, please click: https://www.multivu.com/teamlab_phenomena/9331451-en-gb-teamlab-phenomena-abu-dhabi-opens-saadiyat-cultural-district
On 17 April, the grand opening celebration welcomed distinguished guests and cultural leaders, featuring a specially composed performance by renowned Italian pianist and composer Ludovico Einaudi. Set against the venue’s unique architecture, the score was paired with a dramatic display of 6,000 synchronised drones and pyrotechnics, curated to celebrate the new milestone for Saadiyat Cultural District, and reflect the connection between art, technology and imagination.
H.E. Mohamed Khalifa Al Mubarak, Chairman of the Department of Culture and Tourism – Abu Dhabi, said: “teamLab Phenomena Abu Dhabi is a groundbreaking cultural landmark that redefines immersive art experiences on a global scale. It embodies a bold vision that pushes the boundaries of creativity, technology, and human perception, offering visitors an experience unlike any other. Together with our partner, teamLab, we take great pride in bringing this pioneering concept to life, reinforcing our commitment to shaping world-class experiences that inspire, engage, and contribute to Abu Dhabi’s cultural legacy. Saadiyat Cultural District is a cultural landmark of global significance, bringing together the world’s greatest minds and institutions to foster dialogue, inspire creativity, and shape a more connected future.”
Following the opening ceremony, guests were immersed within newly unveiled teamLab Phenomena Abu Dhabi exhibits, meandering between its inspiring artistic installations, interacting with the dynamic artworks, and experiencing the connection between art, technology and natural phenomena.
Toshiyuki Inoko, Founder of teamLab, said: “The artworks in teamLab Phenomena do not exist independently but are created by the environment which produces the various phenomena that creates the artworks. Objects such as stones and man-made creations maintain a stable structure independently. A stone, for instance, will remain unchanged even if placed in a sealed box, isolated from the outside world. In contrast, a vortex in the ocean will vanish in an instant if removed from its environment. Unlike a stone, a vortex does not sustain itself; it evolves with the surrounding currents, formed by water flowing continuously from the outside to the inside and from the inside to the outside of the vortex, changing along with the flow. Moreover, the boundaries of its existence are ambiguous, and there is no material distinction between the vortex and its surroundings.
“The unique environment produces the phenomena, and the environment maintains the existence of the structure. Let us call that existence Environmental Phenomena. The artwork is inseparable from the environment and changes along with the environment. This concept transcends the various conventional notions of existence by physical forms. Even if people immerse themselves physically into the artwork, the artwork will remain intact, capable of naturally restoring itself even if disrupted. However, when the environment is not sustained, the artwork will disappear. The boundaries of the artwork are ambiguous and continuous with the environment. Perhaps, people’s consciousness will expand from the artwork itself to the environment beyond.”
Spanning 17,000 square metres, teamLab Phenomena Abu Dhabi has been developed by the internationally acclaimed art collective teamLab, in collaboration with the Department of Culture and Tourism – Abu Dhabi (DCT Abu Dhabi). The multi-sensory art experience reflects the emirate’s unwavering commitment to fostering creativity and cultural innovation on a global scale, and it presents massive transformative artworks that each blend art, science and technology in groundbreaking ways.
teamLab Phenomena Abu Dhabi is designed to explore and transcend the limits of every guest’s imagination. Each artwork within the unique, purpose-built venue will evolve over time through the interplay of light, sound and movement. Unlike artworks at traditional galleries, visitors will discover exhibits that are fluid, existing in a dynamic relationship with their environment. Each artwork responds to guests’ actions and natural changes in the environment, creating a living, breathing art experience, unlike any other.
Comprising two distinct Wet and Dry areas, guests will be immersed in a series of mesmerising visuals, vibrant landscapes and interactive installations that dissolve the boundaries between art and audience. Every moment offers a new philosophical experience, ensuring that each visitor experience is unique.
In the Dry area, visitors will encounter a variety of artworks that encourage interaction, responding to their movements and actions to create a unique connection between guests and the installations. As they move into the Wet area, guests will follow a dedicated walkway leading them into an exciting realm filled with fluid, hands-on experiences that further deepen their connection with the art.
teamLab Phenomena Abu Dhabi is a key addition to Saadiyat Cultural District, which upon completion will be the largest concentration of world-leading cultural and educational institutions. The District is home to an unparalleled lineup of museums and cultural landmarks, including Louvre Abu Dhabi; the upcoming Zayed National Museum, the national museum of the UAE; Guggenheim Abu Dhabi, featuring a global collection of modern and contemporary art that reflects the diversity of cultures and trends from around the world; and Natural History Museum Abu Dhabi, telling the story of life on earth and the origins of our universe.
The addition of teamLab Phenomena reinforces Abu Dhabi’s position as a global cultural epicentre, offering visitors a unique and transformative experience while showcasing its commitment to creativity, innovation and cultural collaboration on a global scale.
For more information and to purchase tickets: www.teamlababudhabi.com
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Tyger Capital and Credgenics join hands to redefine collections management with innovative tech solutions
- Leverage Machine Learning insights backed communications approach
- Facilitate digital enablement of field team and offer integrated payments
NEW DELHI, April 18, 2025 /PRNewswire/ — Tyger Capital, India’s leading non-banking financial company (NBFC), has joined hands with Credgenics, the leading provider of SaaS-based collections and debt resolution technology solutions worldwide. This technology collaboration marks a significant stride towards reshaping the debt collections landscape, leveraging Credgenics’ comprehensive suite of solutions to streamline and optimize Tyger Capital’s loan collections management process.
At Tyger Capital, Credgenics’ AI powered SaaS based platform will help adopt a data-insights backed personalized approach for communications with borrowers across multiple digital channels including WhatsApp, SMS, and emails. With Credgenics CG Collect, the mobile app for field collection teams, the last mile operations will be digitized to unlock higher productivity and operational efficiency.
Commenting on the partnership, Rajaram Manian B, Chief Risk Officer of Tyger Capital, said, “We are excited to leverage Credgenics technology solutions in collections as we are committed to deliver unparalleled financial services powered by cutting-edge technologies and customer-centric approaches. This collaboration aligns with our mantra ‘Customer first’ and our focus on providing exceptional service to our customers while optimizing our operations through innovation and digital transformation.”
Credgenics technology platform will optimize field team operations, enable seamless collection transaction reconciliations, provide digitized customer visit management, and provide real-time tracking capabilities. Credgenics Billzy payments platform will facilitate borrowers to make digital loan payments swiftly, securely, and conveniently. Adoption of cutting-edge solutions from Credgenics promises higher response rates, accelerated debt resolutions, and reduced operational costs, positioning Tyger Capital at the forefront of customer service excellence.
Rishabh Goel, Co-Founder and CEO of Credgenics, said, “Our engagement with Tyger Capital is an extremely valuable addition to our customer base from the NBFC segment. We are confident that Credgenics’ comprehensive solutions will tremendously enhance the collection management process at Tyger Capital. With our focus on continual innovation, enhanced customer experience and strict adherence to regulatory compliance, we aim to deliver significant business value at Tyger Capital.”
The collaboration between Credgenics and Tyger Capital is set to drive a transformative shift in collection management and debt resolution by leveraging cutting-edge technologies. This strategic partnership will enable both companies to deliver enhanced value to their customers while driving sustainable growth and profitability.
About Credgenics
Credgenics is the leading provider of Loan Collections and Debt Resolution technology platforms to Banks, Non-banking finance companies, FinTechs, and ARCs worldwide. The AI-powered SaaS-based platform has been recognized as the #1 Best Selling Loan Collections Platform in India by IBS Intelligence in their Annual Sales League Table for three years consecutively. Credgenics caters to the end-to-end collection lifecycle for retail and SME / MSME debt and works with over 150 customers. It handled more than 98 million retail loan accounts worth over USD 250 Billion in FY24 for collections and has sent over 1.7 billion omni-channel communications. With Credgenics, lenders have increased resolution rates by 20%, improved collections by 25%, reduced collections costs by 40%, reduced collections time by 30%, and improved legal process efficiencies by 60%. https://www.credgenics.com/
About Tyger Capital
Tyger Capital Private Limited is a Non-Banking Financial Company (NBFC) headquartered in Mumbai, Maharashtra, India. Established in 2016, the company commenced lending operations in April 2017 with a mission to support entrepreneurship by providing financial solutions tailored for Micro, Small, and Medium Enterprises (MSMEs) and rural development. Tyger Capital is dedicated to be the most “economical” and “convenient” lender – Instant disbursement to underserved communities and small businesses. The company’s vision is to be a trusted financial partner that educates, guides, and supports customers, fostering active participation in the financial ecosystem. Tyger Capital has a robust presence with a network of 250 branches across nine states: Andhra Pradesh, Gujarat, Karnataka, Madhya Pradesh, Maharashtra, Rajasthan, Tamil Nadu, Telangana, and Uttar Pradesh. This extensive reach enables the company to effectively serve a diverse clientele. Tyger Capital is committed to empowering entrepreneurs and fostering economic growth through its comprehensive financial solutions and customer-centric approach. https://tygercapital.in/
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Herbalife India Launches New Podcast Series – Live Your Best Life, Unscripted
The debut episode explores holistic wellness, mental resilience, and performance strategies with renowned sports scientist and high-performance coach Shayamal Vallabhjee.
BENGALURU, India, April 17, 2025 /PRNewswire/ — In a world where wellness conversations are often reduced to diet fads and fitness trends, Herbalife India, a premier health and wellness company, community and platform is bringing a refreshing change with the launch of its brand-new podcast series — ‘Live Your Best Life, Unscripted’.
Designed as an honest, inspiring, and insightful platform, the podcast brings together experts, athletes, and thought leaders to share their journeys, insights, and lessons on holistic well-being — not just physical fitness, but also mental resilience and emotional balance.
The series is hosted by Ajay Khanna, Managing Director of Herbalife India, who leads engaging conversations with personalities known for their contributions to health, wellness, and performance.
Kicking off the series is an insightful episode featuring Shayamal Vallabhjee — a celebrated sports scientist, high-performance coach, and author. With over two decades of experience working with elite athletes and teams worldwide, Shayamal offers a fresh perspective on what it really means to live a balanced life.
From his experiences growing up in South Africa to living as a monk, Shayamal shares how discipline, mental strength, and spirituality shape both performance and overall well-being. The conversation also explores the role of technology, the importance of gut health, mindful eating, and perhaps most importantly — self-compassion.
Speaking on the launch of the podcast, Ajay Khanna, Managing Director, Herbalife India, said:
“At Herbalife, we believe wellness is a lifelong journey—one that goes beyond counting calories or tracking fitness goals. Live Your Best Life, Unscripted is our way of fostering real, thought-provoking conversations that inspire people to embrace a more holistic approach to health. Through this podcast, we hope to empower listeners with insights from experts and changemakers, encouraging them to prioritize not just physical well-being, but also mental resilience and emotional balance.”
The podcast is available in both video and audio formats — making it easy for viewers to tune in from anywhere.
Watch the Full Episode on Herbalife’s YouTube Channel
Prefer Audio? Listen to the Podcast here: Apple Podcast:
https://podcasts.apple.com/us/podcast/live-your-best-life-unscripted/id1808386057
Spotify Podcast: https://open.spotify.com/episode/5dn8QAS0Ods24TVLxyeYsS?si=oeD3ZkONQFqzzs4aeU1w6A
Amazon Music:
This is just the beginning. New episodes of Live Your Best Life, Unscripted will continue to feature inspiring voices from the world of sports, nutrition, and wellness.
Herbalife
(NYSE: HLF) is a premier health and wellness company, community and platform that has been changing people’s lives with great nutrition products and a business opportunity for its independent distributors since 1980. The Company offers science-backed food products to consumers in more than 90 markets through entrepreneurial distributors who provide one-on-one coaching and a supportive community that inspires their customers to embrace a healthier, more active lifestyle to live their best life.
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teamLab Phenomena Abu Dhabi opens its doors to the public in Saadiyat Cultural District
Tyger Capital and Credgenics join hands to redefine collections management with innovative tech solutions
Herbalife India Launches New Podcast Series – Live Your Best Life, Unscripted
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